Short Title: Int. J. Mech. Eng. Robot. Res.
Frequency: Bimonthly
Average Days to Accept: 100 days
Impact Factor 2025:
0.9
CiteScore 2025:
SJR 2025:
Professor of School of Engineering, Design and Built Environment, Western Sydney University, Australia. His research interests cover Industry 4.0, Additive Manufacturing, Advanced Engineering Materials and Structures (Metals and Composites), Multi-scale Modelling of Materials and Structures, Metal Forming and Metal Surface Treatment.
2026-06-18
2026-06-04
Manuscript received January 9, 2026; revised February 26, 2026; accepted April 23, 2026; July 10, 2026
Abstract—The procedure for reconstituting powdered (lyophilized) medications in hospital settings involves shaking the medication with a diluent, which poses risks of ergonomic injuries to healthcare personnel and incomplete dosing of patients. This study addresses the development of a low-cost mixing device designed for the reconstitution of powdered medications in hospital settings, with the aim of evaluating the reliability of the process compared to manual methods, ensuring the occupational safety of nursing staff, and achieving more consistent solutions. To achieve this objective, the requirements of the healthcare personnel at Hospital III Goyeneche were compiled. The device was then designed using a crank-and-crank mechanism and 3D modeling software; this mechanism allows the powder vials to be shaken more effectively than with the manual method. The prototype was experimentally evaluated using vials of ceftriaxone and PIPTABAC. The results show that the device improves the consistency of the dilution, reduces the need for manual intervention by healthcare personnel, and increases the reliability of the process for the evaluated medications, at a cost that is affordable for hospital settings with limited resources, demonstrating that it is possible to improve the procedure using a low-cost solution compared to high-cost automated systems.Keywords—design, vials, dilution, hospital settings, reconstitution, 3D modeling, lyophilized Cite: Franco Pareja Molina, Carlos Rodríguez Davila, Erick Valdeiglesias Flores, Yuri L. Silva, and Daniela Ponte, "Design and Evaluation of a Device for Reconstitution of Lyophilized Medications in the Hospital Setting," International Journal of Mechanical Engineering and Robotics Research, Vol. 15, No. 4, pp. 353-361, 2026. doi: 10.18178/ijmerr.15.4.353-361Copyright © 2026 by the authors. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
